Crosslinking Kits
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CovalX Crosslinking Kits
Because of the tendency of these complexes to dissociate during analysis, the analysis of protein complexes by mass spectrometry is typically labor intensive. CovalX has developed a method for the easy and fast analysis of protein complexes using High-Mass MALDI mass spectrometry coupled with chemical crosslinking. The first step of the analysis is to stabilize the noncovalent complexes of interest using the CovalX dedicated cross-linking reagents and protocols. After stabilization, the sample is ready for direct analysis by High-Mass ToF mass spectrometry.
To effectively analyze intact protein complexes by High-Mass MALDI ToF mass spectrometry, it is crucial to stabilize specifically the complexes with highly efficient cross-linking reagents. CovalX has developed dedicated reagent and buffers to prepare non-covalent protein complexes for High-Mass MALDI analysis. To increase cross-linking efficiency, CovalX’s reagents contain cocktails of cross-linkers with different spacer lengths able to covalently bind specific protein complexes with the highest efficiency. The specificity of CovalX cross-linking reagents allows you to covalently stabilize linked protein complexes even in contaminated or unpurified samples.
MALDI MS Analysis Kits and Reagents for Protein Interactions:
| MALDI MS Analysis Kits and Reagents | Mass Range | Part No. |
|---|---|---|
| K50 MALDI MS Analysis Kit | 0-50 kDa | W2010k50 |
| K100 MALDI MS Analysis Kit | 20-100 kDa | W2010k100 |
| K200 MALDI MS Analysis Kit | 100-1000 kDa | W2010k200 |
| R50 Stabilizer Reagent | 0-50 kDa | W2010R50 |
| R100 Stabilizer Reagent | 20-100 kDa | W2010R100 |
| R200 Stabilizer Reagent | 100-1000 kDa | W2010R200 |
To learn more or order our crosslinking kits
Contact Us, Email us at info@covalx.com, call us at +1(617) 297 2263
CovalX Crosslinking Kits Brochure